|
| Status |
Public on Jul 20, 2011 |
| Title |
Genome-wide analysis distinguishes hyperglycemia regulated epigenetic signatures of primary vascular cells (gene expression) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We report that hyperglycemia-mediated induction of genes and pathways associated to endothelial dysfunction occur through modulation of acetylated H3K9/K14 inversely correlated with methyl-CpG content.
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| |
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| Overall design |
Examination of H3K9/K14 histone acetylation and DNA methylation in hyperglycemic conditions.
see GSE29251 for histone acetylation and DNA methylation
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| |
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| Contributor(s) |
Pirola L, Balcerczyk A, Tothill R, Haviv I, Kaspi A, Lunke S, Karagiannis T, Tonna S, Kowalczyk A, Beresford-Smith B, Zieman M, Kelong M, Hongyu Z, Jinfeng S, Zhu J, El-Osta A |
| Citation(s) |
21890681 |
| Submission date |
Jul 19, 2011 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Assam El-Osta |
| Organization name |
Baker Heart and Diabetes Institute
|
| Lab |
Human Epigenetics
|
| Street address |
75 Commercial Road
|
| City |
Melbourne |
| ZIP/Postal code |
3004 |
| Country |
Australia |
| |
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| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
|
| Samples (12)
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| Relations |
| BioProject |
PRJNA144309 |
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