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Series GSE31341 Query DataSets for GSE31341
Status Public on Aug 19, 2011
Title The Phytoestrogen Genistein Is a Tissue-Specific Androgen Receptor Modulator
Organism Mus musculus
Experiment type Expression profiling by array
Summary We report that the phytoestrogen genistein acts as a tissue-specific androgen receptor modulator in mouse using a novel androgen reporter mouse line and gene expression profiling. Genistein is a partial androgen agonist/antagonist in prostate, brain, and testis but not in skeletal muscle or lung. Gene expression profiling has been done from prostates of intact and castrated male mice treated with genistein or vehicle. Gene expression profiling was also done from prostates of estradiol-treated intact male mice.
 
Overall design Gene expression profiling from prostates of castrated and intact male mice after 5-day genistein- or vehicle-treatment or after 4-day estradiol- or vehicle-treatment.
 
Contributor(s) Pihlajamaa P, Zhang F, Saarinen L, Mikkonen L, Hautaniemi S, Jänne OA
Citation(s) 21878517
Submission date Aug 11, 2011
Last update date Jan 16, 2019
Contact name Olli A. Jänne
E-mail(s) olli.janne@helsinki.fi
Phone +358919125040
Organization name University of Helsinki
Department Inst. of Biomedicine/Physiology
Lab Androgen Receptor Laboratory
Street address Haartmaninkatu-8
City Helsinki
ZIP/Postal code FI-00014
Country Finland
 
Platforms (1)
GPL6887 Illumina MouseWG-6 v2.0 expression beadchip
Samples (21)
GSM777282 Castrated + vehicle rep1 [Genistein expt]
GSM777283 Castrated + vehicle rep2 [Genistein expt]
GSM777284 Castrated + vehicle rep3 [Genistein expt]
Relations
BioProject PRJNA145925

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE31341_RAW.tar 15.8 Mb (http)(custom) TAR
GSE31341_non-normalized_Estradiol.txt.gz 1.7 Mb (ftp)(http) TXT
GSE31341_non-normalized_Genistein.txt.gz 2.2 Mb (ftp)(http) TXT
Processed data included within Sample table
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