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Status |
Public on Aug 17, 2012 |
Title |
Progesterone and estrogen receptors segregate into different cell subpopulations in the normal human breast |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
|
Summary |
Gene expression profiles of normal human mammary epithelial cell subsets enriched for luminal or myoepithelial characteristics on the basis of EpCAM and CD49f expression. Transcription profiles were compared between luminal- and myoepithelial-enriched human MEC subsets following 3D culture from 4 individuals. Gene expression profiles of normal human mammary epithelial cell subsets enriched for mature, luminal progenitor or bipotent progenitor-enriched characteristics on the bais of CD49f, MUC1, CD10, CD133 and Thy1 expression Transcription profiles were compared between unsorted, mature, luminal progenitor-enriched and bipotent progenitor-enriched human MEC subsets following 3D culture from 2 individuals.
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Overall design |
Four replicates of luminal-enriched human MECs and 3 replicates of myoepithelial-enriched MECs Transcription profiles of two replicates of unsorted, mature, luminal progenitor-enriched and bipotent progenitor-enriched human MEC subsets were analysed following 3D culture
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Citation(s) |
22580007 |
Submission date |
Aug 16, 2011 |
Last update date |
Aug 16, 2018 |
Contact name |
Heidi Hilton |
E-mail(s) |
heidi.hilton@sydney.edu.au
|
Phone |
612 9845 9066
|
Organization name |
University of Sydney
|
Department |
Westmead Institute for Cancer Research
|
Lab |
Breast Group
|
Street address |
Darcy Rd, Westmead
|
City |
Sydney |
State/province |
NSW |
ZIP/Postal code |
2145 |
Country |
Australia |
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Platforms (1) |
GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
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Samples (15)
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Relations |
BioProject |
PRJNA145787 |