 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on May 27, 2015 |
| Title |
Orphan Nuclear Receptors ERRα/γ are competence factors for somatic cell reprogramming |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We report the expression profiles of the nuclear receptor family of transcription factors, known regulators of metabolism, during iPSC generation. Unique but overlapping expression patterns were found in iPSCs derived from adipose derived stem cells (ADSCs) and embryonic fibroblasts (human and mouse) that correlate with developmental transitions in the cell.
|
| |
|
| Overall design |
Total RNA was obtained from human embryonic fibroblast IMR90 cells (IMR90s) untreated, transduced with GFP or with the four reprogramming factors (Oct4, Sox2, Klf4, c-Myc; OSKM) at day 5 of reprogramming.
|
| |
|
| Contributor(s) |
Yu RT, Kida YS, Evans RM |
| Citation(s) |
25865501 |
| Submission date |
Aug 29, 2011 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Ruth T Yu |
| Organization name |
Salk Institute
|
| Department |
Gene Expression Lab
|
| Lab |
Ronald Evans
|
| Street address |
10010 N Torrey Pines Rd
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (6)
|
|
| Relations |
| BioProject |
PRJNA145619 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE31704_RAW.tar |
26.2 Mb |
(http)(custom) |
TAR |
| GSE31704_non-normalized.txt.gz |
1.9 Mb |
(ftp)(http) |
TXT |
| Processed data included within Sample table |
|
|
|
|
 |
Less...
More...