|
| Status |
Public on Jun 13, 2013 |
| Title |
Molecular profiling of human mammary gland links breast cancer risk to a p27+ cell population with progenitor characteristics |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
|
| Summary |
Gene expression, DNA and histone methylation profiles were performed on multiple cell types purified from normal human nulliparous and parous breast tissue using SAGE-seq, MSDK-seq and ChIP-seq [GSE26141].
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| |
|
| Overall design |
SAGE-seq, MSDK-seq and ChIP-seq libraries were made from individual cell types and integrated to find a comprehensive view of parity associated changes.
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| |
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| Contributor(s) |
Choudhury SA, Polyak K, Maruyama R |
| Citation(s) |
23770079 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| P01 CA080111 |
The Role of P27 in Breast Epithelial Progenitors and Breast Cancer Risk |
DANA-FARBER CANCER INSTITUTE |
KORNELIA POLYAK |
| P50 CA089393 |
The Role of Stromal Cells and Stromal-Epithelial Interaction in the Early Stages |
DANA-FARBER CANCER INSTITUTE |
KORNELIA POLYAK |
|
| Submission date |
Sep 09, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Kornelia Polyak |
| E-mail(s) |
kornelia_polyak@dfci.harvard.edu
|
| Phone |
617-632-2106
|
| Organization name |
Dana-Farber Cancer Institute
|
| Department |
Medical Oncology
|
| Lab |
Polyak
|
| Street address |
450 Brookline Ave
|
| City |
Boston |
| State/province |
MA |
| ZIP/Postal code |
02215 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL9052 |
Illumina Genome Analyzer (Homo sapiens) |
|
| Samples (42)
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| Relations |
| BioProject |
PRJNA147521 |
| SRA |
SRP008218 |
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