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| Status |
Public on Nov 14, 2011 |
| Title |
Transcriptome of early postnatal brain development of eIF2B-R132H/R132H mutant mice relative to wild-types. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Genome-wide mRNA expression in brains of wild-type and eIF2B-R132H/R132H mutant mice (Geva et al., BRAIN 133 (8), 2010) profiled at postnatal (P) days 1, 18 and 21 to reflect the early proliferative stage prior to white matter establishment (P1) and the peak of oligodendrocye differentiation and myelin synthesis (P18 and P21).
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| Overall design |
3 biological replicates (whole brain without the cerebellum) from each wild-type and eIF2B-R132H/R132H mutant mice at 3 postnatal (P) days 1, 18 and 21 were used for RNA extraction and hybridization on Affymetrix microarrays.
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| Contributor(s) |
Marom L, Ulitsky I, Shamir R, Elroy-Stein O |
| Citation(s) |
22073122 |
| Submission date |
Sep 18, 2011 |
| Last update date |
Mar 04, 2019 |
| Contact name |
Liraz Marom |
| Organization name |
Tel Aviv University
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| Department |
Cell Research and Immunology
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| Lab |
Orna Elroy-Stein
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| Street address |
Department of Cell Research and Immunology Tel Aviv University
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| City |
Tel Aviv |
| ZIP/Postal code |
69978 |
| Country |
Israel |
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| Platforms (1) |
| GPL6246 |
[MoGene-1_0-st] Affymetrix Mouse Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (18)
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| GSM797851 |
wild-type brain at P1, biological rep1 |
| GSM797852 |
wild-type brain at P1, biological rep2 |
| GSM797853 |
wild-type brain at P1, biological rep3 |
| GSM797854 |
eIF2B R132H/R132H mutant brain at P1, biological rep1 |
| GSM797855 |
eIF2B R132H/R132H mutant brain at P1, biological rep2 |
| GSM797856 |
eIF2B R132H/R132H mutant brain at P1, biological rep3 |
| GSM797857 |
wild-type brain at P18, biological rep1 |
| GSM797858 |
wild-type brain at P18, biological rep2 |
| GSM797859 |
wild-type brain at P18, biological rep3 |
| GSM797860 |
eIF2B R132H/R132H mutant brain at P18, biological rep1 |
| GSM797861 |
eIF2B R132H/R132H mutant brain at P18, biological rep2 |
| GSM797862 |
eIF2B R132H/R132H mutant brain at P18, biological rep3 |
| GSM797863 |
wild-type brain at P21, biological rep1 |
| GSM797864 |
wild-type brain at P21, biological rep2 |
| GSM797865 |
wild-type brain at P21, biological rep3 |
| GSM797866 |
eIF2B R132H/R132H mutant brain at P21, biological rep1 |
| GSM797867 |
eIF2B R132H/R132H mutant brain at P21, biological rep2 |
| GSM797868 |
eIF2B R132H/R132H mutant brain at P21, biological rep3 |
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| Relations |
| BioProject |
PRJNA147387 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE32201_RAW.tar |
66.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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