|
| Status |
Public on Dec 07, 2011 |
| Title |
Tumor-Derived G-CSF Facilitates Neoplastic Growth through a Granulocytic Myeloid-Derived Suppressor Cell-Dependent Mechanism |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Global gene expression studies were performed to determine whether the granulocytic-like MDSC populations from G-CSF treated mice resembled those of tumor-bearing (TB) mice more so than those of the non-tumor-bearing control (i.e., WT) at a molecular level.
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| |
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| Overall design |
Splenic CD11b+Gr-1high cell populations from WT, G-CSF-treated or 4T1-TB mice were purified in two independent experiments by flow cytometry (> 98% purity) and subjected to whole genome expression profiling using Illumina microarrays.
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| |
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| Contributor(s) |
Waight JD, Hu Q, Liu S, Abrams SI |
| Citation(s) |
22110722 |
| Submission date |
Sep 19, 2011 |
| Last update date |
Jan 16, 2019 |
| Contact name |
song liu |
| Organization name |
Roswell Park Cancer Institute
|
| Street address |
Elm and Carlton Streets
|
| City |
Buffalo |
| State/province |
NY |
| ZIP/Postal code |
14263 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL6887 |
Illumina MouseWG-6 v2.0 expression beadchip |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA147477 |
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