|
| Status |
Public on Jan 28, 2013 |
| Title |
Using DNA methylation to detect dysplasia/early neoplasia in Barrett's carcinogenesis |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
Dysplasia and early cancer are hard to detect in endoscopic biopsies and hence this study was carried out to evaluate the biomarker potential of DNA methylation to detect dyspasia and early cancer in Barrett's esophaghus patients. Bisulfite converted genomic DNA was hybridized onto Illumina 27k methylation arrays.
|
| |
|
| Overall design |
22 Barrett's esophagus (BE) and 2 Duodenum vs. 24 esophageal adenocarcinoma (EAC)
|
| |
|
| Contributor(s) |
Alvi MA, Fitzgerald RC |
| Citation(s) |
23243219 |
| Submission date |
Oct 12, 2011 |
| Last update date |
Jan 02, 2015 |
| Contact name |
Muhammad Abdullah Alvi |
| E-mail(s) |
abdullah.alvi@cantab.net
|
| Organization name |
University of Cambridge
|
| Street address |
Addenbrooke's site
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 0XZ |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL8490 |
Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2) |
|
| Samples (48)
|
|
| Relations |
| BioProject |
PRJNA146489 |
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