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| Status |
Public on Oct 01, 2012 |
| Title |
Genome wide DNA methylation analysis of leukemia and reprogrammed leukemia cells (gene expression) |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
We analyzed the methylation pattern of a well characterized leukemia cell line, named K562. Furthermore, we decided to investigate how the malignant epiegenome change during the reprogramming process
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| |
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| Overall design |
We used Affymatrix expression microarrays analysis to investigate the relation between expression and methylation in leukemia and reprogrammed leukemia (LiPS). We show that the erasure of the epigenetic aberrancies have functional consequences on leukemia phenotype
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| |
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| Contributor(s) |
Amabile G, Di Ruscio A, Ebralidze A, Wongphayak S, Benoukraf T |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Oct 25, 2011 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Touati Benoukraf |
| E-mail(s) |
tbenoukraf@mun.ca
|
| Phone |
+1 (709) 864-6671
|
| Organization name |
Memorial University of Newfoundland
|
| Department |
Faculty of Medicine, Discipline of Genetics
|
| Street address |
Craig L. Dobbin Genetics Research Centre,
|
| City |
St. John's |
| State/province |
NL |
| ZIP/Postal code |
A1B 3V6 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE33231 |
Genome wide DNA methylation analysis of leukemia and reprogrammed leukemia cells |
|
| Relations |
| BioProject |
PRJNA156615 |
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