|
| Status |
Public on May 01, 2013 |
| Title |
Small RNA analysis of wildtype Mouse embryo and Adar1 null mouse embryo at E11.0 and E11.5 together with mRNA-seq results of E11.5 |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
Non-coding RNA profiling by high throughput sequencing
|
| Summary |
Adar1 is an essential gene for mouse embryonic development. Adar1 null mouse embryos dies around E11.5 because of massive apoptosis.
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| |
|
| Overall design |
Small RNA: 4 samples examined: wild type E11.0, ADAR1 null E11.0, wild type E11.5, ADAR1 null E11.5, mRNA-seq: wild type E11.5, ADAR1 null E11.5.
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| |
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| Contributor(s) |
Ota H, Sakurai M, Gupta R, Valente L, Wulff B, Ariyoshi K, Iizasa H, Davuluri RV, Nishikura K |
| Citation(s) |
23622242 |
| Submission date |
Nov 04, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Kazuko Nishikura |
| Organization name |
The Wistar Institute
|
| Department |
Gene Expression & Regulation
|
| Street address |
3601 Spruce Street
|
| City |
Philadelphia |
| State/province |
Pennsylvania |
| ZIP/Postal code |
19104 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
|
| Samples (6)
|
| GSM828140 |
Small RNAs from Mouse Embyro Day11 |
| GSM828141 |
Small RNAs from ADAR1 KO Mouse Embyro Day11 |
| GSM828142 |
Small RNAs from Mouse Embyro Day11.5 |
| GSM828143 |
Small RNAs from ADAR1 KO Mouse Embyro Day11.5 |
| GSM828144 |
mRNAs from WildType Embryo Day11.5 |
| GSM828145 |
mRNAs from ADAR1 KO Embryo Day11.5 |
|
| This SubSeries is part of SuperSeries: |
| GSE43192 |
ADAR1 forms a complex with Dicer to promote microRNA processing and RNA-induced gene silencing |
|
| Relations |
| SRA |
SRP009192 |
| BioProject |
PRJNA148757 |
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