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| Status |
Public on Nov 11, 2011 |
| Title |
Genomic exploration of monozygotic twins discordant (MZD) for schizophrenia uncovers de novo mutations (DNM) and reveals candidate genes |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
SNP genotyping by SNP array
|
| Summary |
We examined six pairs of monozygotic twins discordant (MZD) for schizophrenia and identified copy number variation (CNV) and single nucleotide polymorphism (SNP) differences between affected and unaffected co-twins using the Affymetrix Genome Wide SNP 6.0.
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| Overall design |
Affymetrix SNP arrays were performed according to the manufacurer's protocol on DNA extracted from whole blood
CNV analysis was done using Affymetrix Genotyping Console 4.0 and Partek Genotyping Suite
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| |
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| Contributor(s) |
Castellani CA, Singh SM |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Nov 09, 2011 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Christina A Castellani |
| E-mail(s) |
ccastel3@uwo.ca
|
| Organization name |
The University of Western Ontario
|
| Department |
Biology
|
| Street address |
Biological and Geological Sciences Building
|
| City |
London |
| State/province |
Ontario |
| ZIP/Postal code |
N6A5B7 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA148543 |
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