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| Status |
Public on Nov 22, 2011 |
| Title |
MERLION LUNG CANCER STUDY_2_DNA |
| Organism |
Homo sapiens |
| Experiment type |
Genome variation profiling by SNP array
|
| Summary |
East-Asian (EA) patients with Non Small Cell Lung Cancer (NSCLC) are associated with a high proportion of non-smoking women, EGFR activating somatic mutations, and clinical responses to tyrosine kinase inhibitors. We identify copy number alterations specific to EA and Western European (WE) NSCLCs and conducted an integrative analysis using transcritomic data for identifying copy-number-driven candidate genes.
Samples were hybridized to Affymetrix Genome-Wide Human SNP 6.0 arrays according to the manufacturer’s specifications in the same center.
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| Overall design |
226 lung adenocarcinomas (90 East-Asian and 136 Western-European) were analyzed for copy-number aberrations (CNAs) using a common high resolution SNP microarray platform.
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| Contributor(s) |
Broët P, Dalmasso C, Tan E, Alifano M, Zhang S, Wu J, Lee M, Régnard J, Lim D, Koong H, Agasthian T, Miller LD, Lim E, Camilleri-Broët S, Tan P |
| Citation(s) |
21521776 |
| Submission date |
Nov 21, 2011 |
| Last update date |
Nov 27, 2018 |
| Contact name |
Cyril Dalmasso |
| E-mail(s) |
cyril.dalmasso@genopole.cnrs.fr
|
| Organization name |
Université d'Evry Val d'Essonne
|
| Department |
Mathématiques
|
| Lab |
Statistique et Génome
|
| Street address |
23 bd de France
|
| City |
Evry |
| ZIP/Postal code |
91037 |
| Country |
France |
| |
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| Platforms (1) |
| GPL6801 |
[GenomeWideSNP_6] Affymetrix Genome-Wide Human SNP 6.0 Array |
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| Samples (226)
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| Relations |
| BioProject |
PRJNA148175 |
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