|
| Status |
Public on Jan 04, 2012 |
| Title |
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
Methylation profiling by high throughput sequencing
|
| Summary |
This SuperSeries is composed of the SubSeries listed below.
|
| |
|
| Overall design |
Refer to individual Series
|
| |
|
| Contributor(s) |
Jothi R, Hu G, Freudenberg J |
| Citation(s) |
22210859 |
| Submission date |
Dec 08, 2011 |
| Last update date |
May 15, 2019 |
| Contact name |
Raja Jothi |
| E-mail(s) |
jothi@mail.nih.gov
|
| Organization name |
National Institutes of Health
|
| Department |
National Institute of Environmental Health Sciences
|
| Lab |
Systems Biology
|
| Street address |
111 TW Alexander Drive; A314
|
| City |
RTP |
| State/province |
NC |
| ZIP/Postal code |
27709 |
| Country |
USA |
| |
|
| Platforms (2) |
| GPL9250 |
Illumina Genome Analyzer II (Mus musculus) |
| GPL14661 |
[Mouse430_2_Mm_EntrezG] Affymetrix GeneChip Mouse Genome 430 2.0 Array [Brainarray Version 13] |
|
| Samples (12)
|
| GSM846066 |
Tet1-KD ES cells siRNA #1 96hr, rep2 |
| GSM846067 |
Tet1-KD ES cells siRNA #2 96hr, rep1 |
| GSM846068 |
Tet1-KD ES cells siRNA #2 96hr, rep2 |
| GSM846069 |
Tet1-KD ES cells siRNA #1 48hr, rep1 |
| GSM846070 |
Tet1-KD ES cells siRNA #1 48hr, rep2 |
| GSM857135 |
Control ES cells 96hr, untreated DNA-Seq |
| GSM857136 |
Control ES cells 96hr, 5hmC glucosyltransferase treated DNA-Seq |
| GSM857137 |
Tet1-KD ES cells 96hr, untreated DNA-Seq |
| GSM857138 |
Tet1-KD ES cells 96hr, 5hmC glucosyltransferase treated DNA-Seq |
|
| This SuperSeries is composed of the following SubSeries: |
| GSE34886 |
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity [expression profiling] |
| GSE34887 |
Acute depletion of Tet1-dependent 5-hydroxymethylcytosine levels impairs LIF/Stat3 signaling and results in loss of embryonic stem cell identity [MRE-seq] |
|
| Relations |
| BioProject |
PRJNA149737 |
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