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| Status |
Public on Jan 01, 2013 |
| Title |
Genome-wide analysis of human pluripotent cells after kd/oe of SNF5 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of global gene expression by SNF5 level change in human pluripotent and differentiated cells. The core subunit of BAF complex SNF5 is at the nexus of the link between chromatin remodeling and tumor suppression. We demonstrated a role for the remodeler SNF5 as a key executor in regulating pluripotency gene networks during differentiation by using loss and gain of function experiments followed by gene-expression arrays.
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| Overall design |
Total RNA obtained from pluripotent state, differentiated state, absense of SNF5 and overexpression of SNF5
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| |
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| Contributor(s) |
Peter J |
| Citation(s) |
23637628 |
| Submission date |
Feb 17, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
jueng soo You |
| Organization name |
USC
|
| Department |
Norris Comprehensive Cancer Center
|
| Lab |
Peter Jones
|
| Street address |
1441 Eastlake Ave
|
| City |
LA |
| State/province |
CA |
| ZIP/Postal code |
90042 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
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| Samples (10)
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| This SubSeries is part of SuperSeries: |
| GSE36140 |
SNF5 is an essential executor of epigenetic regulation in pluripotency and differentiation |
|
| Relations |
| BioProject |
PRJNA155691 |
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