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| Status |
Public on Sep 01, 2012 |
| Title |
Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells [Methylation] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by array
|
| Summary |
Non-small cell lung cancer cell (NSCLC) lines were reprogrammed with Yamanaka's cocktail and their methylome and transcriptome were studied and characterized.
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| |
|
| Overall design |
We compared reprogrammed cells to their respective parent (2 NSCLC and 1 human lung fetal fibroblast) and used H1 as a positive control for pluripotency characteristics. The in vitro differentiated cells were also compared to the reprogrammed cells. All samples have biological triplicates except for differentiated cells.
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| |
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| Citation(s) |
22912920 |
| Submission date |
Feb 17, 2012 |
| Last update date |
Jan 02, 2015 |
| Contact name |
Jason Lai |
| E-mail(s) |
jasonlaikh@gmail.com
|
| Organization name |
Max Planck Institute For Heart and Lung Research
|
| Department |
Developmental Genetics
|
| Lab |
Stainier Lab
|
| Street address |
Ludwigstrasse 43
|
| City |
Bad Nauheim |
| State/province |
Hessen |
| ZIP/Postal code |
61231 |
| Country |
Germany |
| |
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| Platforms (1) |
| GPL8490 |
Illumina HumanMethylation27 BeadChip (HumanMethylation27_270596_v.1.2) |
|
| Samples (24)
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| This SubSeries is part of SuperSeries: |
| GSE35913 |
Reversal of Aberrant Cancer Methylome and Transcriptome upon Direct Reprogramming of Lung Cancer Cells. |
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| Relations |
| BioProject |
PRJNA155697 |
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