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GEO help: Mouse over screen elements for information. |
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| Status |
Public on Mar 02, 2015 |
| Title |
Identification of differentially expressed genes in LBH589-treated cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
To identify the targets of LBH589 treatment, we compared gene expression profiles in three different types of human cancer cell lines (H295R, HeLa and MCF-7her2) with and without LBH589 treatment. Affymetrix microarray analysis was performed to determine changes in gene expression that are unique to LBH treatment.
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| Overall design |
LBH-treated cell lines received 50 nM of LBH589 for 24 hours. DMSO and LBH treatments are in triplicate.
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| Contributor(s) |
Chen S |
| Citation(s) |
23160924 |
| Submission date |
Mar 14, 2012 |
| Last update date |
Jul 26, 2018 |
| Contact name |
Shiuan Chen |
| E-mail(s) |
schen@coh.org
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| Phone |
626-359-8111 x63454
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| Organization name |
City of Hope
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| Department |
Surgical Research
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| Street address |
1500 E Duarte Rd
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| City |
Duarte |
| State/province |
CA |
| ZIP/Postal code |
91010 |
| Country |
USA |
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| Platforms (1) |
| GPL6244 |
[HuGene-1_0-st] Affymetrix Human Gene 1.0 ST Array [transcript (gene) version] |
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| Samples (18)
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| GSM895987 |
H295R Cell Line, Control DMSO Treatment, Replicate 1 |
| GSM895988 |
H295R Cell Line, Control DMSO Treatment, Replicate 2 |
| GSM895989 |
H295R Cell Line, Control DMSO Treatment, Replicate 3 |
| GSM895990 |
H295R Cell Line, LBH Treatment, Replicate 1 |
| GSM895991 |
H295R Cell Line, LBH Treatment, Replicate 2 |
| GSM895992 |
H295R Cell Line, LBH Treatment, Replicate 3 |
| GSM895993 |
HeLa Cell Line, Control DMSO Treatment, Replicate 1 |
| GSM895994 |
HeLa Cell Line, Control DMSO Treatment, Replicate 2 |
| GSM895995 |
HeLa Cell Line, Control DMSO Treatment, Replicate 3 |
| GSM895996 |
HeLa Cell Line, LBH Treatment, Replicate 1 |
| GSM895997 |
HeLa Cell Line, LBH Treatment, Replicate 2 |
| GSM895998 |
HeLa Cell Line, LBH Treatment, Replicate 3 |
| GSM895999 |
MCF7her2 Cell Line, Control DMSO Treatment, Replicate 1 |
| GSM896000 |
MCF7her2 Cell Line, Control DMSO Treatment, Replicate 2 |
| GSM896001 |
MCF7her2 Cell Line, Control DMSO Treatment, Replicate 3 |
| GSM896002 |
MCF7her2 Cell Line, LBH Treatment, Replicate 1 |
| GSM896003 |
MCF7her2 Cell Line, LBH Treatment, Replicate 2 |
| GSM896004 |
MCF7her2 Cell Line, LBH Treatment, Replicate 3 |
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| Relations |
| BioProject |
PRJNA153461 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE36509_RAW.tar |
77.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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