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Status |
Public on Oct 10, 2013 |
Title |
TET2 loss-of-function mutations associate with a DNA hypermethylation signature in diffuse large B-cell lymphoma (DNA methylation) |
Organism |
Homo sapiens |
Experiment type |
Methylation profiling by genome tiling array
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Summary |
Genome wide DNA methylation profiling of patient samples with TET2 mutations and Wild type TET2 status . The Illumina Infinium HumanMethylation 450_15017482_v.1.1 was used to obtain DNA methylation profiles across approximately 482,421 CpGs in fresh frozen lymphoma samples. Samples include 19 TET2 wild type and 12 TET2 mutant samples.
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Overall design |
Bisulphite converted DNA from the 31 samples were hybridised to the Illumina Infinium HM450K Human Methylation Beadchip v1.2
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Contributor(s) |
Asmar F, Punj V, Christensen J, Pedersen MT, Pedersen A, Nielsen AB, Hother C, Ralfkiaer U, Brown PD, Ralfkiaer E, Helin K, Gronbaek K |
Citation(s) |
23831920 |
Submission date |
Apr 17, 2012 |
Last update date |
Mar 22, 2019 |
Contact name |
Vasu Punj |
E-mail(s) |
vasupunj@gmail.com
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Organization name |
USC
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Street address |
Biggy Street
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City |
Los Angeles |
State/province |
CA |
ZIP/Postal code |
90033 |
Country |
USA |
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Platforms (1) |
GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
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Samples (31)
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This SubSeries is part of SuperSeries: |
GSE37365 |
TET2 loss-of-function mutations associate with a DNA hypermethylation signature in diffuse large B-cell lymphoma |
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Relations |
BioProject |
PRJNA159819 |