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| Status |
Public on Oct 01, 2012 |
| Title |
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to Vγ9Vδ2 TCR–expressing cells.
BTN3A1 represents a novel antigen–presenting molecule for the activation of Vγ9Vδ2 TCR–expressing cells which play important roles in human tumor immunity and host defense.
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| Overall design |
3 replicates of 4 cell lines (12 samples total) were analysed. Data was RMA normalized, and genes that expressed above the negative control in all 4 cell lines from chromosome 6 considered for further analysis
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| Contributor(s) |
Mori L, De Libero G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| Submission date |
Apr 27, 2012 |
| Last update date |
Feb 18, 2019 |
| Contact name |
jinmiao chen |
| Organization name |
Singapore Immunology Network
|
| Street address |
Biopolis
|
| City |
Singapore |
| ZIP/Postal code |
138648 |
| Country |
Singapore |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA162417 |
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