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Status |
Public on Oct 01, 2012 |
Title |
Butyrophilin 3A1 binds phosphorylated antigens and stimulates human TCR γδ cells. |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
We used genetic approaches to identify butyrophilin 3A1 (BTN3A1) as the molecule that binds and presents phosphorylated antigens to Vγ9Vδ2 TCR–expressing cells. BTN3A1 represents a novel antigen–presenting molecule for the activation of Vγ9Vδ2 TCR–expressing cells which play important roles in human tumor immunity and host defense.
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Overall design |
3 replicates of 4 cell lines (12 samples total) were analysed. Data was RMA normalized, and genes that expressed above the negative control in all 4 cell lines from chromosome 6 considered for further analysis
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Contributor(s) |
Mori L, De Libero G |
Citation missing |
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Submission date |
Apr 27, 2012 |
Last update date |
Feb 18, 2019 |
Contact name |
jinmiao chen |
Organization name |
Singapore Immunology Network
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Street address |
Biopolis
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City |
Singapore |
ZIP/Postal code |
138648 |
Country |
Singapore |
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Platforms (1) |
GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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Samples (12)
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Relations |
BioProject |
PRJNA162417 |