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| Status |
Public on Apr 08, 2013 |
| Title |
FAIRE-seq in primary human megakaryocytes, erythroblasts and monocytes |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Maps of open chromatin in three primary human blood cell types of the myeloid lineage (megakaryocytes, erythroblasts and monocytes) using the formaldehyde-assisted isolation of regulatory elements method followed by next-generation sequencing (FAIRE-seq). We also generated FAIRE-seq data in the megakaryocytic cell line CHRF-288-11. In addition to our data sets, we retrieved FAIRE-seq data for the erythroblastoid cell line K562 (ENCODE Project Consortium 2012) and pancreatic islets (Gaulton et al. 2010), and reanalyzed these data sets using the same methodology.
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| Overall design |
Genome-wide open chromatin profiles of megakaryocytes, erythroblasts and monocytes (in each 2 individuals), pancreatic islets (1 individual), CHRF 288-11 megakaryocytic cells (2 samples) and K562 erythroblastoid cells (2 samples).
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| |
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| Contributor(s) |
Paul DS, Deloukas P |
| Citation(s) |
23570689 |
| Submission date |
May 10, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Dirk Stefan Paul |
| E-mail(s) |
dp5@sanger.ac.uk
|
| Organization name |
Wellcome Trust Sanger Institute
|
| Department |
Human Genetics
|
| Street address |
Wellcome Trust Genome Campus
|
| City |
Hinxton |
| ZIP/Postal code |
CB10 1SA |
| Country |
United Kingdom |
| |
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| Platforms (3) |
| GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
| GPL10999 |
Illumina Genome Analyzer IIx (Homo sapiens) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (6)
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| Relations |
| BioProject |
PRJNA165667 |
| SRA |
SRP013039 |
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