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| Status |
Public on Jul 13, 2012 |
| Title |
Effects of maternal choline intake on placental gene expression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
To explore the influence of maternal choline intake on placental gene expression, we employed whole genome microarray expression profiling to identify genes that were differentially expressed in placental tissues obtained from women consuming two different doses (480 vs. 930 mg/d) of choline throughout the third trimester of pregnancy. Healthy third trimester (gestational week 26-29) pregnant women were randomized to a 12-week choline controlled feeding study. The participants consumed either 480 (n=6) or 930 (n=6) mg choline/d. Full thickness placental samples were collected at delivery to extract RNA and perform the arrays.
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| Overall design |
Healthy third trimester (gestational week 26-29) pregnant women were randomized to a 12-week choline controlled feeding study. The participants consumed either 480 (n=6) or 930 (n=6) mg choline/d for 12 weeks. Placental samples were obtained at delivery
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| Contributor(s) |
Jiang X, Caudill MA, Bar HY, Yan J, West AA, Perry CA |
| Citation(s) |
23195033 |
| Submission date |
Jul 12, 2012 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Xinyin Jiang |
| E-mail(s) |
xj37@cornell.edu
|
| Phone |
6072295536
|
| Organization name |
Cornell University
|
| Department |
Nutritional Sciences
|
| Lab |
Caudill lab
|
| Street address |
241 Kinzelberg Hall, Cornell University
|
| City |
Ithaca |
| State/province |
NY |
| ZIP/Postal code |
14850 |
| Country |
USA |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA170490 |
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