|
| Status |
Public on May 01, 2013 |
| Title |
Expression profile of the endocrine therapy sensitive breast cancer cells MCF7 depleted of PBX1 |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Effect of PBX1 silencing on global gene expression of MCF7 cells stimulated with EGF. The hypothesis tested was that PBX1 is essential for EGF signaling in ERa positive breast cancer cells.
|
| |
|
| Overall design |
Total RNA was obtained from MCF7 cells treated with siRNA directed at PBX1 or an siControl for 72h. Cells were then stimulated with estradiol (EGF) for 3h prior to RNA extraction.
|
| |
|
| Contributor(s) |
Magnani L, Lupien M |
| Citation(s) |
23576735 |
| Submission date |
Jul 17, 2012 |
| Last update date |
Aug 13, 2018 |
| Contact name |
luca magnani |
| E-mail(s) |
luca.magnani@dartmouth.edu
|
| Phone |
6036539932
|
| Fax |
6036539952
|
| Organization name |
Dartmouth College
|
| Department |
Genetics
|
| Lab |
Lupien
|
| Street address |
NCCC one medical drive
|
| City |
Lebanon |
| State/province |
NH |
| ZIP/Postal code |
03756 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (8)
|
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| This SubSeries is part of SuperSeries: |
| GSE39418 |
Genome-wide reprogramming of the chromatin landscape underlies endocrine therapy resistance in breast cancer |
|
| Relations |
| BioProject |
PRJNA170843 |
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