 |
 |
GEO help: Mouse over screen elements for information. |
|
| Status |
Public on Feb 20, 2014 |
| Title |
Chromatin In Situ Proximity (ChrISP): Single-cell analysis of chromatin proximities at a high resolution |
| Organism |
Homo sapiens |
| Experiment type |
Other
|
| Summary |
Current techniques analysing chromatin structures are hampered by either poor resolution of individual cells or high resolution in only large cell populations. Here we describe a new method, ChrISP,which reproducibly scores for chromatin fiber proximities in 3D in single cells with a resolution of < 170 A. Moreover, ChrISP visualizes higher order structures of individual chromosomes in relation to structural hallmarks of interphase nuclei beyond the resolution of the light microscope.
|
| |
|
| Overall design |
Mapping of "unique" (chromosome territory) and "repeated" (COT1) dna used in ChrISP to asses its composition
|
| |
|
| Contributor(s) |
Ohlsson R, Chen X, Fernandez Woodbridge A, Shi C, Gondor A, Yammine S, Sumida N, Ronnlund D, Widengren J |
| Citation(s) |
24641475 |
| Submission date |
Nov 02, 2012 |
| Last update date |
May 15, 2019 |
| Contact name |
Rolf Ohlsson |
| Organization name |
Karolinska Institutet
|
| Department |
Department of Oncology-Pathology
|
| Lab |
Rolf Ohlsson lab
|
| Street address |
Solnavägen 30, 171 64
|
| City |
Stockholm |
| ZIP/Postal code |
171 77 |
| Country |
Sweden |
| |
|
| Platforms (1) |
|
| Samples (2) |
|
| Relations |
| BioProject |
PRJNA178758 |
| SRA |
SRP017023 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE42009_RAW.tar |
640.0 Kb |
(http)(custom) |
TAR (of TAB) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
|
|
|
|
 |
