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| Status |
Public on Jul 02, 2013 |
| Title |
Lactobacillus acidophilus and Helicobacter pylori stimulation of bone marrow derived macrophage |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
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| Summary |
Helicobacter pylori causes chronic gastritis and avoids elimination by the immune system of the infected host. The commensal bacterium Lactobacillus acidophilus has been reported to exert beneficial effects as a supplement during H. pylori eradication therapy.
In the present study, we applied whole genome microarray analysis to compare the immune response induced in murine bone marrow derived macrophages (BMDM) stimulated with L. acidophilus, H. pylori, or with both bacteria in combination
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| Overall design |
Microarray expression profiling was performed to analyze stimulation of bone marrow derived macrophages with Helicobacter pylori 251, Lactobacillus acidophilus NCFM or Lactobacillus acidophilus NCFM co-stimulated with Helicobacter pylori 251 were analyzed 5 hours after infection.
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| Contributor(s) |
Weiss G, Gould J, Forster S, Kaparakis-Liaskos M, Hertzog P |
| Citation(s) |
23760466 |
| Submission date |
Nov 29, 2012 |
| Last update date |
May 10, 2018 |
| Contact name |
Sam Forster |
| Organization name |
Monash University
|
| Department |
Monash Institute
|
| Lab |
Centre for Innate Immunity and Infectious Diseases
|
| Street address |
27 - 31 Wright Street
|
| City |
Clayton |
| State/province |
Victoria |
| ZIP/Postal code |
3168 |
| Country |
Australia |
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| Platforms (1) |
| GPL4134 |
Agilent-014868 Whole Mouse Genome Microarray 4x44K G4122F (Feature Number version) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA182370 |
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