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| Status |
Public on Jan 01, 2014 |
| Title |
Peripheral circulating mRNA profiling in predicting the pathological response to neoadjuvant chemoradiation for esophageal squamous cell carcinoma |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of peripheral circulating mRNA expression levels in patients undergoing neoadjuvant chemoradiation for esophageal squamous cell carcinoma. The hypothesis test was that chemoradiation alters the circulating mRNA expression profiles and the profiling is predictive of pathological response. Results provide information on the response of circulating mRNAs to chemoradiation and identify novel biomarkers or targets in esophageal squamous cell carcinoma.
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| Overall design |
Total RNA obtained from peripheral whole blood before and after neoadjuvant chemoradiation in patients with esophageal squamous cell carcinoma. 21 patients with 42 samples were analyzed. The expression profiles from pathological complete responders were compared to non-complete responders.
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| |
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| Contributor(s) |
Hsu F, Cheng JC, Chuang EY, Lee J |
| Citation(s) |
25980316 |
| Submission date |
Jan 15, 2013 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Feng-Ming Hsu |
| E-mail(s) |
hsufengming@ntuh.gov.tw
|
| Organization name |
National Taiwan University Hospital
|
| Department |
Department of Oncology
|
| Street address |
No.7, Chung Shan S. Rd.
|
| City |
Taipei |
| ZIP/Postal code |
10002 |
| Country |
Taiwan |
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| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
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| Samples (42)
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| Relations |
| BioProject |
PRJNA186639 |
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