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Status |
Public on Nov 20, 2013 |
Title |
Identification of differentially expressed small RNAs of colon cancer stem cells. |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
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Summary |
Colorectal carcinoma (CRC) is one of the most common cancers worldwide. Re-evaluating our current knowledge on CRC and developing novel therapeutic strategies is still crucial. Accumulating evidence suggests that cancer cells possess characters reminiscent of those of normal stem cells. Unveiling small RNAs responsible for cell stemness and chemoradioresistance should eventually lead to the development of novel therapeutic approaches.
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Overall design |
Expression profiles of parental CRC cells and cancer spheres expanded under stem cell medium cultivation were generated for identifying key regulators.
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Contributor(s) |
Hwang W, Wang H |
Citation(s) |
24561623 |
Submission date |
Jan 28, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Wei-Lun Hwang |
Organization name |
National Yang Ming Chiao Tung University
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Department |
Department of Biotechnology and Laboratory Science in Medicine
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Lab |
WLH LAB
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Street address |
No.155, Sec.2, Linong Street
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City |
Taipei |
ZIP/Postal code |
11221 |
Country |
Taiwan |
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Platforms (1) |
GPL9115 |
Illumina Genome Analyzer II (Homo sapiens) |
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Samples (4)
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This SubSeries is part of SuperSeries: |
GSE43802 |
Characterization of Snail-associated small RNAs in colon cancer cells |
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Relations |
BioProject |
PRJNA188068 |
SRA |
SRP018284 |