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| Status |
Public on Jun 01, 2013 |
| Title |
Geometric control of the coronary artery endothelial cell transcriptome following serum starvation |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Analysis of the effects of cell shape on human coronary artery endothelial cell transcription. The hypothesis is that defined alterations in endothelial cell shape uniquely affect the endothelial transcriptome.
Human coronary artery endothelial cells were plated onto spatially defined micropatterns (Cytoo) forcing them to conform to Disc, Crossbow, H, Y, or L shapes. As a control, human coronary artery endothelial cells were plated on non-restrictive areas of the Cytoo growth plate. Cells were serum starved for 48 hours prior to mRNA collection.
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| |
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| Overall design |
RNA was collected after 48 hours growth on the restricted or non-restricted growth patterns and subjected to whole genome microarray analysis.
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| |
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| Contributor(s) |
Bryan BA, Mitchell DC |
| Citation(s) |
23802622 |
| Submission date |
Feb 08, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Brad Allen Bryan |
| E-mail(s) |
brad.bryan@ttuhsc.edu
|
| Organization name |
Texas Tech University Health Sciences Center
|
| Department |
Biomedical Sciences
|
| Street address |
5001 El Paso Drive
|
| City |
El Paso |
| State/province |
Texas |
| ZIP/Postal code |
79905 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (17)
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| This SubSeries is part of SuperSeries: |
| GSE44168 |
Geometric control of the coronary artery endothelial cell transcriptome |
|
| Relations |
| BioProject |
PRJNA188937 |
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