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| Status |
Public on Apr 01, 2014 |
| Title |
Whole-genome landscape of histone H2AX and γ-H2AX along with related factors in activated cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
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| Summary |
Phosphorylation of the histone variant H2AX forms γ-H2AX, which serves as a marker of DNA repair response. Here we provide ChIP-seq-based maps of histone H2AX, γ-H2AX, H2AZ, INO80, SRCAP, and RNA polymerase II in activated T cells. Matched data for H2AX and γ-H2AX in resting T cells and Jurkat cancer T cells are available in GSE25577.
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| Overall design |
CD4+ T cells were stimulated in two different ways (IL-2 alone or IL-2 plus anti-CD3 and anti-CD28), and H2AX, γ-H2AX, H2AZ, INO80, and SRCAP profiles were examined by ChIP-seq
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| Contributor(s) |
Seo J, Choi JK |
| Citation(s) |
24163101 |
| Submission date |
Feb 13, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Jungmin Seo |
| Organization name |
Omicsis.Inc
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| Department |
Bioinformatics Research Institute
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| Street address |
#211, BVC, KRIBB, Eoung-dong, Yuseong-gu
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| City |
Daejeon |
| ZIP/Postal code |
305-806 |
| Country |
South Korea |
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| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA189444 |
| SRA |
SRP018668 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE44309_RAW.tar |
18.9 Gb |
(http)(custom) |
TAR (of BED) |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data provided as supplementary file |
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