|
| Status |
Public on May 06, 2014 |
| Title |
Genomic binding profile of TAL1 in human Endothelial Colony-Forming Cells |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
|
| Summary |
Endothelial colony-forming cells (ECFCs) have been reported as promising cells for regenerative medicine thanks to their angiorepair properties. Transcription factors are primary determinants of the functional capacity of the cells and TAL1 has been shown as a critical regulator of endothelial lineage in both development and adult life. However, only few (three) TAL1 targets have been identified so far in mouse and human endothelial cells. This ChIP-seq experiment was designed to identify genome binding/occupancy of TAL1 by ChIP and high throughput sequencing in primary human endothelial stem/progenitor cells.
|
| |
|
| Overall design |
TAL1 ChIP and IgG ChIP (negative control) were performed in crosslinked ECFCs derived from human umbilical cord blood.
|
| |
|
| Contributor(s) |
Palii CG, Pranckeviciene E, Perez-Iratxeta C, Brand M |
| Citation(s) |
24792117 |
| Submission date |
Feb 20, 2013 |
| Last update date |
May 15, 2019 |
| Contact name |
Marjorie Brand |
| E-mail(s) |
karthi.sivaraman@gmail.com, mbrand@ohri.ca
|
| Organization name |
Ottawa Hospital Research Institute
|
| Street address |
501 Smyth Road
|
| City |
Ottawa |
| State/province |
Ontario |
| ZIP/Postal code |
K1H 8L6 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
|
| Samples (2) |
|
| This SubSeries is part of SuperSeries: |
| GSE44546 |
TAL1 in human Endothelial Colony-Forming Cells |
|
| Relations |
| BioProject |
PRJNA190042 |
| SRA |
SRP018795 |
