|
| Status |
Public on Jan 12, 2015 |
| Title |
Genome-wide analysis of SIK2 regulated genes and pathways |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Identification of SIK2 regulated genes and pathways after SIK2 knock-down and overexpression of a wild-type and kinase-dead SIK2. The hypothesis is that SIK2 regulated gene expression via CREB1
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| |
|
| Overall design |
Total RNAs were obtained after SIK2 gene was knocked down with siRNA and after a wild-type SIK2 or a kinase-dead SIK2 construct were over-expressed in LNCaP cells. A control where the cells were treated with a CREB1 inducer (Forskolin) was also included.
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| |
|
| Contributor(s) |
Bon H, Carroll T, Osborne M |
| Citation(s) |
25548099 |
| Submission date |
Apr 02, 2013 |
| Last update date |
Aug 13, 2018 |
| Contact name |
Chandra Chilamakuri |
| E-mail(s) |
datasubmissions@cruk.cam.ac.uk
|
| Organization name |
Cancer Research UK Cambridge Institute
|
| Street address |
Robinson Way
|
| City |
Cambridge |
| ZIP/Postal code |
CB2 0RE |
| Country |
United Kingdom |
| |
|
| Platforms (1) |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (56)
|
|
| Relations |
| BioProject |
PRJNA195915 |
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