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| Status |
Public on Dec 03, 2014 |
| Title |
Transcriptional and post-transcriptional analysis of CD4+ T cell clones deriving from HTLV-1 infected individuals |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
T-cell clones were obtained by limiting dilution culture of PBMC of HTLV-1 carriers. Exon expression profiling was performed using Affymetrix exon array (Affymetrix Human Exon 1.0 ST Array) according to the manufacturer's instructions.
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| Overall design |
The main objectives were to assess whether transcriptional and post-transcriptional modifications associate with HTLV-1 infection in vivo. To this end, T-cell clones, infected or not by HTLV-1, were obtained by limiting dilution culture of PBMC derived from HTLV-1 carriers. Exon expression profiles of cloned T cells was analyzed using Affymetrix exon array (Affymetrix Human Exon 1.0 ST Array) according to the manufacturer's instructions.
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| Contributor(s) |
Thenoz M, VERNIN C, MORTREUX F, CROZE S, LEGRAS-LACHUER C, NAZARET N |
| Citation(s) |
25205102 |
| Submission date |
Apr 30, 2013 |
| Last update date |
Feb 18, 2019 |
| Contact name |
franck mortreux |
| E-mail(s) |
franck.mortreux@ens-lyon.fr
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| Organization name |
oncovirology and Biotherapies, UMR5239, LBMC
|
| Street address |
46 allee d'Italie
|
| City |
lyon |
| ZIP/Postal code |
69000 |
| Country |
France |
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| Platforms (1) |
| GPL5175 |
[HuEx-1_0-st] Affymetrix Human Exon 1.0 ST Array [transcript (gene) version] |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA200718 |
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