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Status |
Public on Jul 27, 2006 |
Title |
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation |
Organism |
Homo sapiens |
Experiment type |
Expression profiling by array
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Summary |
A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. We report the identification and biologic characterization of an LPS-like molecule extracted from the cyanobacterium Oscillatoria Planktothrix FP1 (CyP). Keywords: different ligands
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Overall design |
2 untreated (CTR), 2 treated with LPS at 3h, 2 treated with CyP at 1h, 2 treated with CyP at 3h, 2 treated with LPS + CyP at 3h
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Contributor(s) |
Maccagno A, Monica M, Rinaldi A, Bertoni F, Lanzavecchia A, Carlo R, Sallusto F |
Citation(s) |
16717116 |
Submission date |
May 01, 2006 |
Last update date |
Mar 25, 2019 |
Contact name |
Francesco Bertoni |
E-mail(s) |
francesco.bertoni@ior.usi.ch
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Phone |
+41 91 820 0367
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Organization name |
IOR
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Department |
Lymphoma & Genomics Research Program
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Street address |
Via V. Vela 6
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City |
Bellinzona |
State/province |
Ticino |
ZIP/Postal code |
6500 |
Country |
Switzerland |
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Platforms (1) |
GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
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Samples (10)
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Relations |
BioProject |
PRJNA95695 |