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| Status |
Public on Jun 13, 2013 |
| Title |
Antitumoral activity of acadesine and rituximab in MCL |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Acadesine is a nucleoside analogue with known antileukemic effects in different neoplasms. We investigated the activity of acadesine ne exerts a cytotoxic effect in MCL and synergizes with rituximab supporting clinical examination of this strategy for MCL patients
We used microarrays to detail the gene expression changes in acadesine-, rituximab- and combination-treated tumors.
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| Overall design |
Global RNA expression in tumors treated with acadesine, rituximab and the combination in a xenograft model of MCL (Jeko-1). Tumors were collected 18 days after the initiation of the treatments.
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| Contributor(s) |
Montraveta A, Colomer D |
| Citation(s) |
24519895 |
| Submission date |
Jun 12, 2013 |
| Last update date |
Mar 21, 2019 |
| Contact name |
DOLORS COLOMER |
| E-mail(s) |
dcolomer@clinic.cat
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| Phone |
34 660775688
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| Organization name |
IDIBAPS-HOSPITAL CLINIC
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| Street address |
VILLARROEL 170
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| City |
BARCELONA |
| ZIP/Postal code |
08036 |
| Country |
Spain |
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| Platforms (1) |
| GPL13667 |
[HG-U219] Affymetrix Human Genome U219 Array |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA208230 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE47871_RAW.tar |
26.6 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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