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| Status |
Public on Jun 19, 2013 |
| Title |
Crosstalk between the effects of extracellular vesicles (Evs) and TNF on U937 human monocyte cell line |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Under physiological conditions, extracellular vesicles (EVs) are present simultaneously in the extracellular compartment together with cytokines. Thus, we hypothesized that EVs in combination with cytokines induce different responses of monocyte cells compared to EVs or cytokines alone. Human monocyte U937 cells were incubated with EV-containing or EV-free CCRF human T-cell supernatant, with or without the addition of TNF.
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| Overall design |
U937 cells cultured in EV-free supernatant, supernatant containing CCRF t-cell derived Evs, TNF or both. Each treatment option was measured in 3 replicates.
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| Contributor(s) |
Szabo-Taylor K, Szabo TG, Tarr B, Paloczi K, Eder K, Kittel A, Toth S, Gyorgy B, Pasztoi M, Nemeth A, Osteikoetxea X, Pallinger E, Buzas E |
| Citation(s) |
24705984 |
| Submission date |
Jun 12, 2013 |
| Last update date |
Jan 23, 2019 |
| Contact name |
Katalin Szabo-Taylor |
| Organization name |
Semmelweis University
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| Department |
Department of Genetics, Cell- and Immunobiology
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| Street address |
Nagyvárad tér 4.
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| City |
Budapest |
| ZIP/Postal code |
1089 |
| Country |
Hungary |
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| Platforms (1) |
| GPL6480 |
Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Probe Name version) |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA208846 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE47897_RAW.tar |
25.8 Mb |
(http)(custom) |
TAR (of TXT) |
| Processed data included within Sample table |
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