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| Status |
Public on Jul 03, 2013 |
| Title |
Global epigenomic reconfiguration during mammalian brain development |
| Organisms |
Homo sapiens; Mus musculus |
| Experiment type |
Methylation profiling by high throughput sequencing
Expression profiling by high throughput sequencing
|
| Summary |
Whole-genome single-base resolution methylcytosine and hydroxymethylcytosine maps reveal profound changes that occur during frontal cortex development in humans and mice.
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| |
|
| Overall design |
MethylC-Seq, TAB-Seq, RNA-Seq and hmC-IP (CMS-IP and biotin-glucosyl tagging) from Homo sapiens and Mus musculus frontal cortex tissue and neural sorted cell populations. Additionally, MethylC-Seq was performed on the HUES6 embryonic stem cell line (Homo sapiens).
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| |
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| Contributor(s) |
Lister R, Ecker JR |
| Citation(s) |
23828890, 26030523 |
| Submission date |
Jun 14, 2013 |
| Last update date |
Sep 09, 2019 |
| Contact name |
Joseph R Ecker |
| E-mail(s) |
ecker@salk.edu
|
| Phone |
8584534100
|
| Organization name |
HHMI-Salk-Institute
|
| Department |
Genomic Analysis Laboratory
|
| Lab |
Ecker lab
|
| Street address |
10010 North Torrey Pines Road
|
| City |
La Jolla |
| State/province |
CA |
| ZIP/Postal code |
92037 |
| Country |
USA |
| |
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| Platforms (2) |
| GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
| GPL13112 |
Illumina HiSeq 2000 (Mus musculus) |
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| Samples (65)
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| Relations |
| BioProject |
PRJNA208503 |
| SRA |
SRP026048 |
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