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Status |
Public on Jul 20, 2013 |
Title |
De novo sequencing of circulating microRNAs in locally advanced breast cancer |
Organism |
Homo sapiens |
Experiment type |
Non-coding RNA profiling by high throughput sequencing
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Summary |
MicroRNAs (miRNAs) have been recently detected in the circulation of cancer patients, where they are associated with clinical parameters. Discovery profiling of circulating small RNAs has not been previously reported in breast cancer (BC), and was carried out in this study to identify blood-based small RNA markers of BC clinical outcome.
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Overall design |
The pre-treatment sera of 42 stage II–III locally advanced and inflammatory BC patients who received neoadjuvant chemotherapy (NCT) followed by surgical tumor resection were analyzed for marker identification by deep sequencing all circulating small RNAs.
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Contributor(s) |
Wu X, Wang SE |
Citation missing |
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Submission date |
Jul 19, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Xiwei Wu |
E-mail(s) |
xwu@coh.org
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Organization name |
Beckman Research Institute
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Department |
Molecular and Cellular Biology
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Lab |
Integrative Genomics Core
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Street address |
1500 E Duarte Rd
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City |
Duarte |
State/province |
CA |
ZIP/Postal code |
91010 |
Country |
USA |
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Platforms (1) |
GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
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Samples (42)
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Relations |
BioProject |
PRJNA212733 |
SRA |
SRP027589 |