|
| Status |
Public on Jan 23, 2014 |
| Title |
Effects of YB-1 protein reduction on microRNA abundance in breast cancer cell-lines |
| Platform organism |
synthetic construct |
| Sample organism |
Homo sapiens |
| Experiment type |
Non-coding RNA profiling by array
|
| Summary |
To assess the association of the nucleic acid binding protein yb-1 with mature microRNAs levels in breast cancer. To do this we performed YB-1 siRNA treatement in triplicates alongside an siRNA control
Two breast cancer cell-lines, representative of Luminal A and Basal molecular subtypes were used, MCF7 and MDA-MB-435S.
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| |
|
| Overall design |
Two cell-lines, treated with either siYB-1 or si-Ctrl in triplicate samples.
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| |
|
| Contributor(s) |
Blenkiron C, Lasham A, Print C, Hurley D, Fitzgerald S |
| Citation(s) |
24260353 |
| Submission date |
Aug 22, 2013 |
| Last update date |
May 02, 2017 |
| Contact name |
Cherie Blenkiron |
| E-mail(s) |
c.blenkiron@auckland.ac.nz
|
| Organization name |
University of Auckland
|
| Department |
Surgery
|
| Lab |
ASML
|
| Street address |
Private bag 92019
|
| City |
Auckland |
| ZIP/Postal code |
1142 |
| Country |
New Zealand |
| |
|
| Platforms (1) |
| GPL14613 |
[miRNA-2] Affymetrix Multispecies miRNA-2 Array |
|
| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE50142 |
Links between the Oncoprotein YB-1 and Small Non-Coding RNAs in Breast Cancer |
|
| Relations |
| BioProject |
PRJNA216148 |
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