|
| Status |
Public on Jun 20, 2006 |
| Title |
48h Immobilization in human |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Our results suggest that 48h of immobilization increases expression of mRNA for components of the UPP and MT function while decreasing mRNA and protein for components involved in ECM integrity. We hypothesized that 48h of immobilization would increase gene expression and respective protein products for components of the ubiquitin proteasome pathway (UPP).
Keywords: stimulus or stress design
|
| |
|
| Overall design |
To identify novel pathways involved in the atrophy program activated in response to 48h of limb immobilization in humans.
|
| |
|
| Contributor(s) |
Clarkson P |
| Citation(s) |
16763108 |
| Submission date |
Jun 20, 2006 |
| Last update date |
Oct 01, 2019 |
| Contact name |
Eric P Hoffman |
| E-mail(s) |
ericphoffman@gmail.com
|
| Organization name |
Binghamton University - SUNY
|
| Department |
Pharmaceutical Sciences
|
| Street address |
PO Box 6000
|
| City |
Binghamton |
| State/province |
NY |
| ZIP/Postal code |
13902 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL570 |
[HG-U133_Plus_2] Affymetrix Human Genome U133 Plus 2.0 Array |
|
| Samples (10)
|
|
| Relations |
| BioProject |
PRJNA95375 |
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