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Status |
Public on Sep 30, 2013 |
Title |
Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3’ processing |
Organisms |
Homo sapiens; synthetic construct |
Experiment type |
Expression profiling by high throughput sequencing Other
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Summary |
Our study of CstF64 and CstF64τ revealed both functional overlap and specificity of these two important mRNA 3’ processing factors and provided new insights into the regulatory mechanisms of mRNA 3’ processing.
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Overall design |
CstF64tau iCLIP-seq in HeLa cells; direct RNA sequencing (DRS) of control HeLa cells, CstF64tau-RNAi cells and SELEX-seq for RNA control pool, CstF64 and CstF64tau.
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Contributor(s) |
Yao C, Choi E, Weng L, Xie X, Wan J, Xing Y, J.Moresco J, G.TU P, R.Yates III J, Shi Y |
Citation(s) |
24149845 |
Submission date |
Sep 25, 2013 |
Last update date |
May 15, 2019 |
Contact name |
Yongsheng Shi |
E-mail(s) |
yongshes@uci.edu
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Organization name |
University of California, Irvine
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Street address |
University of California, Irvine B240, Med Sci I
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City |
Irvine |
State/province |
CA |
ZIP/Postal code |
92697 |
Country |
USA |
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Platforms (3) |
GPL11154 |
Illumina HiSeq 2000 (Homo sapiens) |
GPL14761 |
Helicos HeliScope (Homo sapiens) |
GPL15228 |
Illumina HiSeq 2000 (synthetic construct) |
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Samples (5)
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Relations |
BioProject |
PRJNA221564 |
SRA |
SRP030467 |