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Series GSE56960 Query DataSets for GSE56960
Status Public on Mar 14, 2017
Title Caloric-dose responsive genes in blood cells differentiate the metabolic status of obese men
Organism Homo sapiens
Experiment type Expression profiling by array
Summary One current focus of nutrition research is the identification of biomarkers that reflect the impact of food on metabolic processes. As this approach mostly targets the prevention rather than the curing of diseases, novel biomarkers need to be identified. Those should be influenced by the diet already in healthy individuals and be nonetheless indicative, or even predictive, of the potential impact of specific food on the development of metabolic diseases such as obesity.
The blood cell transcriptome of two different population groups after the ingestion of different caloric doses of a high-fat meal was measured by microarray technology.
 
Overall design A human intervention study was conducted including seven normal weight and seven obese subjects who consumed three caloric doses (500, 1000, 1500 kcal) of a high-fat meal. The blood cell transcriptome was measured before (0h) as well as 2h, 4h and 6h after the meal ingestion.
 
Contributor(s) Gille D, Zangger N, Soneson C, Buetikofer U, Delorenzi M, Schwander F, Kopf-Bolanz KA, Chollet M, Walther B, Laederach K, Vergères G
Citation(s) 28319853
Submission date Apr 22, 2014
Last update date Mar 21, 2019
Contact name Doreen Gille
Organization name Agroscope
Street address Schwarzenburgstrasse 161
City Bern
ZIP/Postal code 3003
Country Switzerland
 
Platforms (1)
GPL13667 [HG-U219] Affymetrix Human Genome U219 Array
Samples (168)
GSM1372162 Subject 12, Meal A (500 kcal), Fasting (0h)
GSM1372163 Subject 12, Meal A (500 kcal), Postprandial (2h)
GSM1372164 Subject 12, Meal A (500 kcal), Postprandial (4h)
Relations
BioProject PRJNA245076

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Supplementary file Size Download File type/resource
GSE56960_RAW.tar 325.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table

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