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| Status |
Public on Apr 08, 2015 |
| Title |
Established glioma cell lines prove valuable models for tumour heterogeneity - mediated cellular response studies in vitro |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Both established glioma cells lines U87MG and U373 were used for studying their interactions in the indirect co-cultures. Eventhough both being derived from the glioma tissue, those two cell lines prove morphologically and physiologically disctinct. Therefore their intre-cellular interactions were examined on gene exprexssion level in vitro to observe whether those co-cultures could make for a suitable in vitro cell model mimicking the in vivo glioma tumour heterogeneity.
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| Overall design |
Three biological replicates of four cell set-ups were performed: U87MG monoculture, U373 monoculture, U87MG co-cultured with U373 (in Boyden chambers) and U373 co-cultured with U87MG (in Boyden chambers).
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| Contributor(s) |
Motaln H, Lah TT, Gruden K, Rotter A, van Noorden CJ, Verbovsek U |
| Citation(s) |
25356585, 26517510 |
| Submission date |
Jul 21, 2014 |
| Last update date |
Jul 29, 2019 |
| Contact name |
Ana Rotter |
| E-mail(s) |
ana.rotter@nib.si
|
| Phone |
+38659232940
|
| Organization name |
National Institute of BIology
|
| Department |
Marine Biology Station
|
| Street address |
Fornace 41
|
| City |
Piran |
| ZIP/Postal code |
6330 |
| Country |
Slovenia |
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| Platforms (1) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
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| Samples (12)
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| Relations |
| BioProject |
PRJNA255790 |
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