|
| Status |
Public on Aug 05, 2015 |
| Title |
Transcriptome profiling of deciduas from pre-eclamptic and normotensive pregnancies |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
Genome-wide analysis of decidual transcriptome in pre-eclampsia compared with normotensive controls to find differentially expressed genes/pathways.
Preeclampsia (PE) is a common and serious pregnancy hypertensive disorder with a strong genetic component. The study aims were to use genome-wide analysis of decidual transcriptome in pre-eclampsia compared with normotensive controls to identify differentially expressed biological pathways, and to determine common pathways between the transcriptome and previously identified maternal susceptibility genes.
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| |
|
| Overall design |
Total RNA from decidua basalis obtained from pre-eclamptic and normotensive control patients at Caesarean section
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| |
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| Contributor(s) |
Yong HE, Melton PE, Johnson MP, Freed KA, Kalionis B, Murthi P, Brennecke SP, Keogh RJ, Moses EK |
| Citation(s) |
26010865 |
| Submission date |
Aug 15, 2014 |
| Last update date |
Feb 18, 2019 |
| Contact name |
Eric K Moses |
| Organization name |
The University of Western Australia
|
| Department |
Centre for Genetic Origins of Health and Disease
|
| Lab |
Centre for Genetic Origins of Health and Disease
|
| Street address |
Level 5, Medical Research Foundation (MRF) Building, 50 Murray Street
|
| City |
Perth |
| State/province |
Western Australia |
| ZIP/Postal code |
6000 |
| Country |
Australia |
| |
|
| Platforms (2) |
| GPL6884 |
Illumina HumanWG-6 v3.0 expression beadchip |
| GPL10558 |
Illumina HumanHT-12 V4.0 expression beadchip |
|
| Samples (125)
|
|
| Relations |
| BioProject |
PRJNA258259 |
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