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| Status |
Public on Jul 23, 2015 |
| Title |
14-3-3ζ controls adipocyte progenitor cell cycle and differentiation via Gli3-dependent p27Kip expression |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
14-3-3 proteins facilitate cytoplasmic-nuclear shuttling of transcription factors.Adipocyte differentiation requires the function of critical transcription factors to drive the development of a mature adipocyte. The aim of the study was to investigate if 14-3-3ζ is required for the adipogenic transcriptional program.
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| Overall design |
Examination of the transcriptome in siCon- and si14-3-3ζ-transfected 3T3-L1 cells undergoing differentiation at t=0, 24, and 48 hours.
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| |
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| Contributor(s) |
Lim GE, Johnson JD |
| Citation(s) |
26220403 |
| Submission date |
Aug 26, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Gareth Lim |
| E-mail(s) |
gareth.lim@umontreal.ca
|
| Organization name |
CRCHUM
|
| Street address |
R08.482- 900 rue St Denis
|
| City |
Montreal |
| State/province |
Quebec |
| ZIP/Postal code |
H2X 0A9 |
| Country |
Canada |
| |
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| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
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| Samples (24)
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| Relations |
| BioProject |
PRJNA259415 |
| SRA |
SRP045772 |
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