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| Status |
Public on Sep 01, 2015 |
| Title |
Modified Stat1 Confers Enhanced Interferon Responsiveness and Improved Baseline Antiviral Host Defense |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
U3A cells stably expressing wild-type STAT1 or STAT1-CC were treated with interferon beta (10U/ml) or control for 24 hours to assess effects of stat1 modifications, interferon, and the interaction on gene expression.
Keywords: interferon, STAT1, STAT1-CC, STAT1CC, STAT-1C, antiviral
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| Overall design |
RNA was isolated from stable U3A-STAT1 lines stably expressing wild-type STAT1 or STAT1CC, after 24 hour treatment with interferon beta (10U/ml) or control.
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| Contributor(s) |
Zhang Y, Patel AC, Mao D, Patel DA, Roswit WT, Huang G, McCarthy R, Jin X, Atkinson JJ, Agapov E, Yu J, Yun NE, Paessler S, Lawson TG, Omattage NS, Brett TJ, Holtzman MJ |
| Citation(s) |
26479788 |
| Submission date |
Sep 15, 2014 |
| Last update date |
Aug 16, 2018 |
| Contact name |
Anand Champak Patel |
| E-mail(s) |
acpatelmd@gmail.com
|
| Organization name |
Washington University School of Medicine
|
| Department |
Pulmonary/Critical Care Medicine
|
| Lab |
Patel
|
| Street address |
Campus Box 8116, 660 S. Euclid Ave.
|
| City |
St. Louis |
| State/province |
MO |
| ZIP/Postal code |
63110 |
| Country |
USA |
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| Platforms (1) |
| GPL6947 |
Illumina HumanHT-12 V3.0 expression beadchip |
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| Samples (12)
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| This SubSeries is part of SuperSeries: |
| GSE61421 |
PARP9 and DTX3L in Antiviral Host Defense |
|
| Relations |
| BioProject |
PRJNA261038 |
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