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| Status |
Public on Apr 15, 2015 |
| Title |
Expression data of mice cochlea treated with L-methionine and valproic acid. |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by array
|
| Summary |
Treatment of DBA/2J mice with a combination of L-methionine and valproic acid significantly attenuated progressive hearing loss. We examined gene expression in the whole cochlea of the mice. This study was aimed to detect genes of which change in expression levels were associated with attenuation of progressive hearing loss in the mice.
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| Overall design |
DBA/2J mice at 4 weeks old (untreated_4-weeks, N=5), mice treated with control vehicle (0.1M sodium bicarbonate) for 8 weeks (Control_vehicle_12-weeks, N=5), and mice treated with L-methionine and valproic acid (MET_and_VA_12-weeks, N=6) were analyzed.
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| Contributor(s) |
Mutai H, Miya F, Fujii M, Tsunoda T, Matsunaga T |
| Citation(s) |
25875282, 26484279 |
| Submission date |
Oct 08, 2014 |
| Last update date |
Feb 11, 2019 |
| Contact name |
Fuyuki Miya |
| E-mail(s) |
fmiya@keio.jp
|
| Phone |
+81-3-5363-3890
|
| Organization name |
Keio University
|
| Department |
School of Medicine
|
| Lab |
Center for Medical Genetics
|
| Street address |
35 Shinanomachi, Shinjuku-ku
|
| City |
Tokyo |
| State/province |
Tokyo |
| ZIP/Postal code |
160-8582 |
| Country |
Japan |
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| Platforms (1) |
| GPL1261 |
[Mouse430_2] Affymetrix Mouse Genome 430 2.0 Array |
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| Samples (16)
|
| GSM1520968 |
Mouse cochlea of 4 weeks of age #4 |
| GSM1520969 |
Mouse cochlea of 4 weeks of age #5 |
| GSM1520970 |
Mouse cochlea of 12 weeks of age with control vehicle #1 |
| GSM1520971 |
Mouse cochlea of 12 weeks of age with control vehicle #2 |
| GSM1520972 |
Mouse cochlea of 12 weeks of age with control vehicle #3 |
| GSM1520973 |
Mouse cochlea of 12 weeks of age with control vehicle #4 |
| GSM1520974 |
Mouse cochlea of 12 weeks of age with control vehicle #5 |
| GSM1520975 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #1 |
| GSM1520976 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #2 |
| GSM1520977 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #3 |
| GSM1520978 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #4 |
| GSM1520979 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #5 |
| GSM1520980 |
Mouse cochlea of 12 weeks of age with L-methionine and valproic acid #6 |
|
| Relations |
| BioProject |
PRJNA263368 |
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