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| Status |
Public on Nov 14, 2006 |
| Title |
Expression data from adrenal glands from normoxic and hypoxic neonatal rats |
| Organism |
Rattus norvegicus |
| Experiment type |
Expression profiling by array
|
| Summary |
We hypothesize that changes in adrenal gene expression mediate the increased plasma corticosterone and steroidogenesis in rat pups exposed to hypoxia from birth.
Keywords: effects of hypoxia on adrenal steroidogenesis in the neonatal rat
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| Overall design |
In the current study, rat pups (with their dams) were exposed to hypoxia from birth and compared to pups from normoxic dams fed ad libitum. Adrenal glands were collected from normoxic and hypoxic pups at PD7and pooled (N=24/sample; 4 samples per treatment group) for total RNA extraction. Microarray analysis was performed, followed by verification with real-time PCR. Furthermore, the expression of selected genes involved in adrenal function was analyzed by real-time PCR, regardless of microarray results.
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| Contributor(s) |
Bruder ED, Raff H |
| Citation(s) |
17213367 |
| Submission date |
Nov 08, 2006 |
| Last update date |
Mar 03, 2017 |
| Contact name |
Eric David Bruder |
| E-mail(s) |
eric.bruder@aurora.org
|
| Organization name |
Aurora St. Luke's Medical Center
|
| Department |
Endocrine Research
|
| Street address |
2801 W. KK River Parkway, Suite 245
|
| City |
Milwaukee |
| State/province |
WI |
| ZIP/Postal code |
53215 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL341 |
[RAE230A] Affymetrix Rat Expression 230A Array |
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| Samples (8)
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| Relations |
| BioProject |
PRJNA97523 |
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