|
| Status |
Public on Apr 07, 2015 |
| Title |
RNA-Seq of retina and RPE/choroid tissues from wild type, Abca4 knockout and Abca4 L541P;A1038V knockin mice |
| Organism |
Mus musculus |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report RNA-Seq analysis of the transcriptome of retinas and RPE/choroids from Abca4 knockout, Abca4 L541P;A1038V knockin and control wild type mice in order to better understand changes in gene regulation that could lead to retinal pathology in mice with ABCA4 deficiency/defect.
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| |
|
| Overall design |
Retinal and RPE/choroidal mRNA profiles of 30-day-old wild type (WT), Abca4-/- and Abca4L541P;A1038V/L541P;A1038V mice were generated by RNA-Seq, using Illumina Hiseq 2500
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| |
|
| Contributor(s) |
Zhang N, Palczewski K |
| Citation(s) |
25712131 |
| Submission date |
Dec 02, 2014 |
| Last update date |
May 15, 2019 |
| Contact name |
Ning Zhang |
| Organization name |
Case Western Reserve University
|
| Department |
Pharmacology
|
| Street address |
10900 Euclid Ave.
|
| City |
Cleveland |
| State/province |
OH |
| ZIP/Postal code |
44106 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL17021 |
Illumina HiSeq 2500 (Mus musculus) |
|
| Samples (18)
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|
| Relations |
| BioProject |
PRJNA269047 |
| SRA |
SRP050429 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE63772_RET_FPKMbyGenotype_Genes.txt.gz |
1.0 Mb |
(ftp)(http) |
TXT |
| GSE63772_RET_FPKMbyGenotype_Isoforms.txt.gz |
1.4 Mb |
(ftp)(http) |
TXT |
| GSE63772_RET_GenesDiffExp.txt.gz |
2.2 Mb |
(ftp)(http) |
TXT |
| GSE63772_RET_RAWFPKM_Genes.txt.gz |
2.2 Mb |
(ftp)(http) |
TXT |
| GSE63772_RET_RAWFPKM_Isoforms.txt.gz |
3.1 Mb |
(ftp)(http) |
TXT |
| GSE63772_RNASeq_retina_and_RPE.html.gz |
316.9 Kb |
(ftp)(http) |
HTML |
| GSE63772_RPE_FPKMbyGenotype_Gene.txt.gz |
1.0 Mb |
(ftp)(http) |
TXT |
| GSE63772_RPE_FPKMbyGenotype_Isoforms.txt.gz |
1.5 Mb |
(ftp)(http) |
TXT |
| GSE63772_RPE_GenesDiffExp.txt.gz |
1.6 Mb |
(ftp)(http) |
TXT |
| GSE63772_RPE_RAWFPKM_Genes.txt.gz |
2.3 Mb |
(ftp)(http) |
TXT |
| GSE63772_RPE_RAWFPKM_Isoforms.txt.gz |
3.2 Mb |
(ftp)(http) |
TXT |
| GSE63772_sashimiplot.png.gz |
98.9 Kb |
(ftp)(http) |
PNG |
SRA Run Selector |
| Raw data are available in SRA |
| Processed data are available on Series record |
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