|
| Status |
Public on Jan 19, 2015 |
| Title |
Genetic Variation, Not Cell Type of Origin, Underlies Regulatory Differences in iPSCs [Methylation] |
| Organism |
Homo sapiens |
| Experiment type |
Methylation profiling by genome tiling array
|
| Summary |
Analysis of contribution of cell type of origin and individual to gene expression differences in iPSCs. The hypothesis tested in the present study was that cell type of origin affects iPSC gene expression. Results show that individual has a much stronger effect than cell type of origin on differences between iPSCs derived from multiple individuals.
|
| |
|
| Overall design |
DNA obtained from feeder-free iPSCs derived from multiple individuals and tissues and their corresponding cell type of origin
|
| |
|
| Contributor(s) |
Kagan CL, Banovich NE, Pavlovic BJ, Patterson K, Gallego Romero I, Pritchard JK |
| Citation(s) |
26812582 |
| Submission date |
Jan 19, 2015 |
| Last update date |
Mar 22, 2019 |
| Contact name |
Nicholas E Banovich |
| Organization name |
University of Chicago
|
| Department |
Human Genetics
|
| Lab |
Gilad
|
| Street address |
920 E. 58th Street, CLSC 317
|
| City |
Chicago |
| State/province |
IL |
| ZIP/Postal code |
60453 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL13534 |
Illumina HumanMethylation450 BeadChip (HumanMethylation450_15017482) |
|
| Samples (24)
|
|
| This SubSeries is part of SuperSeries: |
| GSE65079 |
Genetic Variation, Not Cell Type of Origin, Underlies Regulatory Differences in iPSCs |
|
| Relations |
| BioProject |
PRJNA272899 |
Less...
More...