|
| Status |
Public on Dec 08, 2015 |
| Title |
Epigenetic determinants of self-renewal in glioblastoma [ATAC-seq] |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by high throughput sequencing
Other
|
| Summary |
We over-expressed an epigenetic regulator in a glioblastoma (GBM) primary culture from an adult patient. These GBM cells have cancer stem cell phenotypes, as they have self-renewal properties and tumor initiation potential when transplanted in immunocompromised mice. ATAC-seq was performed on cells over-expressing the epigenetic regulator and control cells expressing EGFP.
|
| |
|
| Overall design |
ATAC-Seq on glioblastoma cells that over-express EGFP or an epigenetic regulator.
|
| |
|
| Contributor(s) |
Gallo M, Dirks P, Murison A, Lupien M |
| Citation(s) |
26626085 |
| Submission date |
Apr 07, 2015 |
| Last update date |
May 15, 2019 |
| Contact name |
Alexander James Murison |
| E-mail(s) |
alexander.murison@uhnresearch.ca
|
| Organization name |
University Health Network
|
| Lab |
Dick Lab
|
| Street address |
101 College Street, TMDT room 11-706
|
| City |
Toronto |
| State/province |
Ontario |
| ZIP/Postal code |
M5G 1L7 |
| Country |
Canada |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (12)
|
|
| Relations |
| BioProject |
PRJNA280596 |
| SRA |
SRP056968 |
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