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| Status |
Public on Apr 18, 2015 |
| Title |
Comparison of gene expression levels in parental U87 cells and U87 tumor spheres treated with or without ITE |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
The formation of U87 tumor spheres was associated with expression changes of many genes which was reverted by the treatment with ITE(2-(1'H-indole-3'-carbonyl)-thiazole-4-carboxylic acid methyl ester).
We used DNA microarrays to profile gene expression in U87 tumor spheres treated with ITE and identified distinct classes of up-regulated and down-regulated genes during this process.
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| Overall design |
U87 cells were selected for RNA extraction and hybridization on Affymetrix microarrays. We compared the expression profiles of parental U87 cells, U87 tumor sphere cells treated with vehicle (DMSO) and U87 tumor sphere cells treated with ITE.
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| Contributor(s) |
Ying-Jie W, Bo K |
| Citation(s) |
26059097, 26484269 |
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Bo Kang, Yanwen Zhou, Min Zheng, Ying-Jie Wang. Genome-wide transcriptional profiling of human glioblastoma cells in response to ITE treatment. Genomics Data 5 (2015) 281283. http://dx.doi.org/10.1016/j.gdata.2015.06.025
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| Submission date |
Apr 17, 2015 |
| Last update date |
Aug 23, 2018 |
| Contact name |
Yingjie Wang |
| E-mail(s) |
yingjiewang@zju.edu.cn
|
| Organization name |
Zhejiang University
|
| Department |
Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine
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| Lab |
Zhejiang
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| Street address |
Research Center C701,School of Medicine,Zhejiang University,866 Yuhangtang Road
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| City |
Hangzhou |
| State/province |
Zhejiang |
| ZIP/Postal code |
310058 |
| Country |
China |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (3) |
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| Relations |
| BioProject |
PRJNA281444 |
