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| Status |
Public on Aug 11, 2017 |
| Title |
Expression data from Enterovirus 71 and Coxsackievirus A16 infected SK-N-SH cells |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Both viruses differently express genes at 48 and 72 hours involving cell cycle, cellular damage and inflammatory response
We used microarrays to detail the total gene expression underlying two virus infection in neuronal cells and identified distinct classes of up-regulated genes during this process at specific time.
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| Overall design |
Enterovirus 71 and Coxsackievirus A16 infected SK-N-SH cells at 48 hours and 72 hours were selected for RNA extraction and hybridization on Affymetrix microarrays, respectively. We sought to obtain high number of infected cell populations of SK-N-SH cells at each time point in order to increase the temporal resolution of expression profiles. To that end, we ensured using flow cytometry data for confirmation of more than 60% of SK-N-SH cells are infected by the viruses.
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| Contributor(s) |
Yogarajah T |
| Citation(s) |
28724943, 29263272 |
| Submission date |
Aug 03, 2015 |
| Last update date |
May 23, 2019 |
| Contact name |
THINESSHWARY YOGARAJAH |
| E-mail(s) |
thiki36@yahoo.com
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| Phone |
0379677538
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| Organization name |
university of malaya
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| Department |
PATHOLOGY
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| Lab |
DEVELOPMENTAL LAB 2
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| Street address |
kuala lumpur
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| City |
wilayah persekutuan |
| ZIP/Postal code |
50603 |
| Country |
Malaysia |
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| Platforms (1) |
| GPL15207 |
[PrimeView] Affymetrix Human Gene Expression Array |
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| Samples (18)
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| GSM1842724 |
SK-N-SH cells at 48 hours, biological rep1 |
| GSM1842725 |
SK-N-SH cells at 48 hours, biological rep2 |
| GSM1842726 |
SK-N-SH cells at 48 hours, biological rep3 |
| GSM1842727 |
Enterovirus A71 at 48 hours, biological rep1 |
| GSM1842728 |
Enterovirus A71 at 48 hours, biological rep2 |
| GSM1842729 |
Enterovirus A71 at 48 hours, biological rep3 |
| GSM1842730 |
Coxsackievirus A16 at 48 hours, biological rep1 |
| GSM1842731 |
Coxsackievirus A16 at 48 hours, biological rep2 |
| GSM1842732 |
Coxsackievirus A16 at 48 hours, biological rep3 |
| GSM1842733 |
SK-N-SH cells at 72 hours, biological rep1 |
| GSM1842734 |
SK-N-SH cells at 72 hours, biological rep2 |
| GSM1842735 |
SK-N-SH cells at 72 hours, biological rep3 |
| GSM1842736 |
Enterovirus A71 at 72 hours, biological rep1 |
| GSM1842737 |
Enterovirus A71 at 72 hours, biological rep2 |
| GSM1842738 |
Enterovirus A71 at 72 hours, biological rep3 |
| GSM1842739 |
Coxsackievirus A16 at 72 hours, biological rep1 |
| GSM1842740 |
Coxsackievirus A16 at 72 hours, biological rep2 |
| GSM1842741 |
Coxsackievirus A16 at 72 hours, biological rep3 |
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| Relations |
| BioProject |
PRJNA291774 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE71673_RAW.tar |
38.3 Mb |
(http)(custom) |
TAR (of CEL, CHP) |
| Processed data included within Sample table |
| Processed data provided as supplementary file |
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